Dr. Sharon D'Souza
Dr. Sharon D'souza

About Dr. Sharon D'Souza

Experience

15 years of experience in ophthalmology, with a focus on compassionate, precise care. Trained at St. John's Medical College Hospital and specialized in Cornea & Refractive Surgery.

Expertise

Specialises in management of corneal diseases, cataract and refractive surgery. Performs all types of corneal transplants including DALK, DSEK, DMEK, PK, and femtosecond keratoplasty.

Approach

A PhD holder and global faculty contributor, Dr. Sharon is dedicated to advancing eye care through clinical research, surgical innovation, and personalized patient care.

HONORS & AWARDS

  1. Best paper refractive surgery – AIOS 2024
  2. Best Paper Award – SICCSO 2023
  3. Best Paper and Best Video – Keracon 2022–2023
  4. Young Achiever Award – ISCKRS 2022
  5. International Hero Award – AIOS 2021
  6.  Shiv Prasad Hardia Award for Best Cornea Paper – AIOS 2022
  7. AIOS Silver Award – Indian Journal of Ophthalmology, 2022
  8. Travel Grants – World Ophthalmology congress 2020
  9. Santen grant- Asia Cornea Society 2018

Academic Contributions

A leading voice in national and international ophthalmology.

Invited faculty and presenter at over 40 national and international conferences, including AIOS, KOS, BOS, KERACON, OSW, ARVO, APAO, AAO, and CRS Mexico.

Conducted live surgical demonstrations, instructional courses, and wetlab surgical courses and chaired scientific panels at many conferences.

Co-Organising secretary for Annual national conference of cornea society of India Keracon 2024.

Research & Publications

  1. Using Artificial Intelligence for an Efficient Prediction of Outcomes of Deep Anterior Lamellar Keratoplasty (DALK) in Advanced Keratoconus. Transl Vis Sci Technol. 2025
  2. Understanding the immunology of the ocular surface and its relevance to clinical practice. Indian J Ophthalmol. 2025
  3. Distinct Ocular Surface Microbiome in Keratoconus Patients Correlate With Local Immune Dysregulation. Invest Ophthalmol Vis Sci. 2025
  4. Elevated Neutrophils and reduced NK cells are associated with altered tear molecular signatures and clinical sequelae of chronic ocular Stevens-Johnson Syndrome. Ocul Surf. 2024
  5. Spike sign - To predict the formation of big bubble in deep anterior lamellar keratoplasty in advanced keratoconus. Indian J Ophthalmol. 2024
  6. Demographic profile and clinical characteristics of patients presenting with acute ocular burns. Indian J Ophthalmol. 2023
  7.   Artificial intelligence-based stratification of demographic, ocular surface high-risk factors in progression of keratoconus.           Indian J Ophthalmol. 2023
  8.  Corneal Regeneration Using Gene Therapy Approaches. Cells. 2023
  9. Ocular surface immune cell diversity in dry eye disease. Indian J Ophthalmol. 2023
  10. Role of in vivo confocal microscopy in dry eye disease and eye pain. Indian J Ophthalmol. 2023
  11.  Systemic investigations in dry eye disease. Indian J Ophthalmol. 2023
  12. Fibromyalgia syndrome and the eye-Implications in corneal ultrastructure on confocal microscopy. Indian J Ophthalmol. 2023
  13. A randomized controlled study evaluating outcomes of intense pulsed light and low-level light therapy for treating meibomian gland dysfunction and evaporative dry eye. Indian J Ophthalmol. 2023
  14.  Modulation of mucin secretion using combined polyethylene glycol-propylene glycol topical formulation in a hyperosmotic stress-based explant model. Indian J Ophthalmol. 2023
  15. Effect of maqui-berry extract in dry eye disease - A clinical and molecular analysis. Indian J Ophthalmol. 2023
  16. Type 1-type 2 interferon imbalance in dry eye disease. Indian J Ophthalmol. 2023
  17.  Evaporative dry eye disease due to meibomian gland dysfunction: Preferred practice pattern guidelines for diagnosis and treatment. Indian J Ophthalmol. 2023
  18. Tear biomarkers in dry eye disease: Progress in the last decade. Indian J Ophthalmol. 2023
  19. Ion channels in dry eye disease. Indian J Ophthalmol. 2023
  20. A novel combination of corneal confocal microscopy, clinical features and artificial intelligence for evaluation of ocular surface pain. PLoS One. 2022
  21. Corneal stromal repair and regeneration. Prog Retin Eye Res. 2022
  22.  Altered Ocular Surface Health Status and Tear Film Immune Profile Due to Prolonged Daily Mask Wear in Health Care Workers. Biomedicines. 2022
  23. Impact of tear optics on the repeatability of Pentacam AXL wave and iTrace in measuring anterior segment parameters and aberrations. Indian J Ophthalmol. 2022
  24. Corneal Confocal Microscopy Features and Tear Molecular Profile in Study Participants with Discordance between Ocular Surface Disease Clinical Signs and Discomfort. J Clin Med. 2022
  25. Ocular Surface Infection Mediated Molecular Stress Responses: A Review. Int J Mol Sci. 2022
  26.  Nodular scleritis-a rare presentation of COVID-19 & variation with testing. Am J Ophthalmol Case Rep. 2022
  27.  PACK-CXL vs. antimicrobial therapy for bacterial, fungal, and mixed infectious keratitis: a prospective randomized phase 3 trial. Eye Vis (Lond). 2022
  28. Clinical and Molecular Outcomes After Combined Intense Pulsed Light Therapy With Low-Level Light Therapy in Recalcitrant Evaporative Dry Eye Disease With Meibomian Gland Dysfunction. Cornea. 2021
  29.  Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile. Sci Rep 2021
  30. COVID-19 positivity rate in corneal tissue donors - A cause for concern! Indian J Ophthalmol. 2021
  31.  Efficacy of topical cyclosporine 0.05% and osmoprotective lubricating eye drops in treating dry eye disease and inflammation. Indian J Ophthalmol. 2021
  32. Global Ophthalmology Practice Patterns during COVID-19 Pandemic and Lockdown. Ophthalmic Epidemiol. 2021
  33. Altered ocular surface immune cell profile in patients with dry eye disease. Ocul Surf. 2021
  34. The Role of Biomarkers in Keratoconus Pathogenesis and Diagnosis. Published – book chapter Springer 2022
  35.  Simultaneous Topography-Guided PRK/CXL Versus Topography-Assisted PTK/CXL: 1-Year Prospective Outcomes in Keratoconic Eyes. J Refract Surg. 2021 
  36. Evaluating the safety and efficacy of compression sutures with intracameral perfluoropropane (C3F8) in the management of acute corneal hydrops. Int Ophthalmol. 2021
  37. Biochemical Markers and Alterations in Keratoconus. Asia Pac J Ophthalmol (Phila). 2020
  38. Photorefractive keratectomy (PRK) Prediction, Examination, tReatment, Follow-up, Evaluation, Chronic Treatment (PERFECT) protocol - A new algorithmic approach for managing post PRK haze. Indian J Ophthalmol. 2020
  39.  Algorithmic approach to diagnosis and management of post-refractive surgery dry eye disease. Indian J Ophthalmol. 2020
  40. Genistein-Calcitriol Mitigates Hyperosmotic Stress-Induced TonEBP, CFTR Dysfunction, VDR Degradation and Inflammation in Dry Eye Disease. Clin Transl Sci. 2020
  41. Sanitizer aerosol-driven ocular surface disease (SADOSD)-A COVID-19 repercussion? Indian J Ophthalmol. 2020
  42.  Tele-consultations in the wake of COVID-19 - Suggested guidelines for clinical ophthalmology. Indian J Ophthalmol. 2020
  43. Descemet's membrane detachment: A novel concept in diagnosis and classification. Am J Ophthalmol. 2020
  44. All India Ophthalmological Society - Eye Bank Association of India consensus statement on guidelines for cornea and eyebanking during COVID-19 era. Indian J Ophthalmol. 2020
  45. Potential ocular and systemic COVID-19 prophylaxis approaches for healthcare professionals. Indian J Ophthalmol. 2020
  46.  Relevance of IgE, allergy and eye rubbing in the pathogenesis and management of Keratoconus. Indian J Ophthalmol. 2020
  47. What ophthalmologists should know about conjunctivitis in Covid-19 pandemic? Indian J Ophthalmol. 2020
  48.  Study of tear film optics and its impact on quality of vision. Indian J Ophthalmol. 2020
  49. Distinct ocular surface soluble factor profile in human corneal dystrophies. Ocul Surf. 2019
  50. Trehalose augments autophagy to mitigate stress induced inflammation in human corneal cells. Ocul Surf. 2019
  51.  Dysregulated tear fluid associated nociception-associated factors, corneal dendritic cell density and vitamin D levels in Evaporative Dry eye. Invest Ophthalmol Vis Sci. 2019
  52.  Pain management after photorefractive keratectomy. J Cataract Refract Surg. 2019
  53.  Late onset Descemet’s membrane detachment 20 years after penetrating keratoplasty.
  54. Comparative Analysis of Two Femtosecond LASIK Platforms Using iTRAQ Quantitative Proteomics. Invest Ophthalmol Vis Sci. 2014
  55. Practical issues concerning tear protein assays in dry eye. Eye Vis (Lond). 2014
  56. Decision making nomogram for intrastromal corneal ring segments in keratoconus. Indian J Ophthalmol. 2014
  57.  WaveLight FS200 vs Hansatome LASIK: Intraoperative Determination of Flap Characteristics and Predictability by Hand-held Bioptigen Spectral Domain Ophthalmic Imaging System. J Refract Surg. 2012
  58. LASIK Flaps. In: Spectral-Domain Optical Coherence Tomography Imaging in the eye. India: Elsevier; 2013
  59. LASIK – Epithelial Ingrowth. In: Spectral-Domain Optical Coherence Tomography Imaging in the eye. India: Elsevier; 2013
  60. LASIK complications – Interface fluid syndrome in a steroid responder. In: Spectral-Domain Optical Coherence Tomography Imaging in the eye. India: Elsevier; 2013
  61. Intrastromal corneal ring segments for management of keratoconus. Indian J Ophthalmol. 2013
  62.  Topography-guided custom ablation treatment for treatment of keratoconus. Indian J Ophthalmol. 2013
  63. Retinoblastoma in patients with regressed retinopathy of prematurity. Indian J Ophthalmol. 2011
  64. Neurologic Disorder. Masquerading as Post pregnancy Progression of Keratoconus. Int J Kerat Ect Cor Dis. 2012